EVER Pharma Launches Room-Temperature-Stable Carbetocin to Improve Access to Postpartum Haemorrhage Prevention

Postpartum haemorrhage (PPH) is the world’s leading direct cause of maternal death. It affects around 27 million women every year and causes nearly 43,000 deaths, most of which could be prevented.¹ EVER Pharma today announced the launch of Carbetocin EVER Pharma in Europe and international markets for the prevention of PPH due to uterine atony after Caesarean section or vaginal birth.²

Uterine atony, where the uterus does not contract properly after childbirth, is the most common cause of PPH. Carbetocin is a long-acting analogue of oxytocin. A single injection produces a firm uterine contraction within approximately two minutes and maintains uterine tone for several hours, reducing the need for continuous oxytocin infusion or repeat uterotonic dosing.²

The WHO recommends a uterotonic for every woman giving birth.³ In practice, until the introduction of carbetocin this was not easy, because oxytocin generally has to be stored in a refrigerator and discarded if it has been kept out of the cold for too long. Carbetocin EVER Pharma does not need refrigeration and can be stored below 30 °C.² Hospitals can keep it right where it is needed, in the delivery room, the operating theatre or the emergency trolley, instead of in a pharmacy fridge. There is no need to monitor cold storage or throw away stock after a temperature excursion, and transport and stock management become simpler. This is particularly helpful for smaller maternity units and for places where a reliable cold chain is hard to maintain. As it is given as a single injection, no infusion equipment is needed.

“No woman should lose her life to preventable bleeding after childbirth,” said Georges Kahwati, CEO of EVER Pharma. “By bringing Carbetocin EVER Pharma to healthcare professionals across Europe and international markets, we are expanding access to an effective uterotonic that can be stored where it is needed most and administered quickly when every minute counts.”

Carbetocin EVER Pharma is available in ampoules and vials. The launch strengthens EVER Pharma’s commitment to women’s health and builds on the company’s long-standing expertise in sterile injectable medicines. Further market launches are planned.