{"id":258,"date":"2021-03-30T14:07:07","date_gmt":"2021-03-30T12:07:07","guid":{"rendered":"https:\/\/www.everpharma.com\/ita\/products\/paclitaxel\/"},"modified":"2021-03-30T14:07:07","modified_gmt":"2021-03-30T12:07:07","slug":"paclitaxel","status":"publish","type":"product","link":"https:\/\/www.everpharma.com\/ita\/en\/products\/paclitaxel\/","title":{"rendered":"Paclitaxel"},"content":{"rendered":"\n
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Dosage Form<\/strong><\/strong><\/td>Concentrate for solution for infusion<\/td><\/tr>
Strength<\/strong><\/strong><\/td>6 mg\/ml<\/td><\/tr>
Strength per Unit<\/strong><\/strong><\/strong><\/td>30 mg\/5 ml, 100 mg\/16.7 ml, 300 mg\/50 ml<\/td><\/tr>
ATC Code <\/strong><\/td>L01CD01<\/td><\/tr>
Drug Class<\/strong><\/strong><\/td>Taxane<\/td><\/tr>
Indication<\/strong><\/td>Ovarian cancer:<\/strong>
In first line chemotherapy of ovarian cancer, paclitaxel is indicated for the treatment of patients with advanced disease or a
residual disease (> 1cm) after initial laparotomy, in combination with cisplatin.
In second-line chemotherapy of ovarian cancer, paclitaxel is indicated in the treatment of metastatic carcinoma of the
ovary after failure of standard platinum based therapy.
Breast cancer:<\/strong>
In the adjuvant setting, paclitaxel is indicated for the treatment of patients with node-positive breast carcinoma following
anthracycline and cyclophosphamide (AC) therapy. Adjuvant treatment with paclitaxel should be regarded as an alternative
to extended AC therapy.
Paclitaxel is indicated for the initial treatment of locally advanced or metastatic breast cancer either in combination with an
anthracycline in patients for whom anthracycline therapy is suitable, or in combination with trastuzumab, in patients who
over-express human epidermal growth factor receptor 2 (HER-2) at a 3+ level as determined by immunohistochemistry
and for whom an anthracycline is not suitable (see section 4.4 and 5.1)
As a single agent, treatment of metastatic carcinoma of the breast in patients who have failed to respond adequately to
standard treatment with anthracyclines or in whom anthracycline therapy has not been appropriate.
Advanced non-small cell lung cancer (NSCLC):<\/strong>
Paclitaxel, in combination with cisplatin, is indicated for the treatment of non-small cell lung cancer in patients who are
not candidates for potentially curative surgical intervention and\/or radiation therapy.
AIDS-related Kaposi’s sarcoma (KS):<\/strong>
Paclitaxel is indicated for the treatment of patients with advanced AIDS-related Kaposi’s sarcoma who have failed prior
liposomal anthracycline therapy.
Limited efficacy data supports this indication; a summary of the relevant studies is shown in section 5.1.<\/td><\/tr><\/tbody><\/table><\/figure>\n<\/div>\n<\/div>\n<\/div><\/div>\n\n\n\n
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Paclitaxel EVER Pharma is a prescription medication. Information for healthcare professionals only.<\/em><\/em>
See the Summary of Product Characteristics for full information about the medication.<\/em><\/em><\/p>\n\n\n\n

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<\/p>\n","protected":false},"excerpt":{"rendered":"

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